Scientific Publications

MetaFight partners prepared all along the project, publications relative to their research activities achieved within the MetaFight project. The publications reported here below concern mainly the second period of the project: July 2009 - December 2010 and also publications issued after the project ends.

• Coló GP, Hernández-Varas P, Lock J, Bartolomé RA, Arellano-Sánchez N, Strömblad S, Teixidó J. Focal adhesion disassembly is regulated by a RIAM to MEK-1 pathway. J Cell Sci. 2012 Sep 3. [Epub ahead of print], PMID:22946047.

• Castro-Castro A., Sauzeau V., Ojeda V., Navarro-Lerida I., Muriel O., Couceiro J.R., Pimentel-Muiños F.X., del Pozo M.A., and Bustelo X.R. Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation. EMBO J. 2011 Aug 26; doi: 10.1038/emboj.2011.310.

• Pablo Hernández-Varas, Georgina P. Coló, Ruben A. Bartolomé, Andrew Paterson, Iria Medraño-Fernández, Nohemí Arellano-Sánchez, Carlos Cabañas, Paloma Sánchez-Mateos, Esther M. Lafuente,, Vassiliki A. Boussiotis, Staffan Strömblad and Joaquin Teixidó, Rap1-GTP-interacting adaptor molecule (RIAM) protein controls invasion and growth of melanoma cells., J.Bio Chem, 2011 May 27, PMID: 21454517.

• Cabodi S, Camacho-Leal MdP, Di Stefano P and Defilippi P., Integrin signalling adaptors: not only figurants in the cancer story. Nat Rev Cancer. 2010 Dec;10(12):858-70. Epub 2010 Nov 24.

• Tornillo G, Bisaro B, Camacho-Leal MD, Galiè M, Provero P, Di Stefano P, Turco E, Defilippi P, Cabodi S., p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1., Eur J Cell Biol. 2010 Oct 18. [Epub ahead of print], PMID: 20961652.

• Cabodi S, Di Stefano P, Leal Mdel P, Tinnirello A, Bisaro B, Morello V, Damiano L, Aramu S, Repetto D, Tornillo G, Defilippi P., Integrins and signal transduction., AdExp Med Biol. 2010;674:43-54. Review., PMID: 20549939.

• Li Z, Lock JG, Olofsson H, Kowalewski JM, Teller S, Liu Y, Zhang H, Strömblad S., Integrin-mediated cell attachment induces a PAK4-dependent feedback loop regulating cell adhesion through modified integrin alpha v beta 5 clustering and turnover. Mol Biol Cell. 2010 Oct;21(19):3317-29. Epub 2010 Aug 18., PMID: 20719960.

• Bustelo Xosé R, A transcriptional crosstalk between RhoA and cMyc inhibits the RhoA/Rockdependent cytoskeleton, July/August 2010, Small GTPases 1: 69-74, DOI:10.4161/sgtp.1.1.12986.

• Karaköse E, Schiller HB, Fässler R., The kindlins at a glance., J Cell Sci. 2010 Jul 15;123(Pt 14):2353-6. No abstract available. PMID: 20592181 [PubMed - in process].

• Le Dévédec SE, Yan K, de Bont H, Ghotra V, Truong H, Danen EH, Verbeek F, van de Water B., Systems microscopy approaches to understand cancer cell migration and metastasis. Cell Mol Life Sci. 2010 Oct;67(19):3219-40. Epub 2010 Jun 18. Review. PMID: 20556632.

• Cabodi S, Tinnirello A, Bisaro B, Tornillo G, del Pilar Camacho-Leal M, Forni G, Cojoca R, Iezzi M, Amici A, Montan i M, Eva A, Di Stefano P, Muthuswamy SK, Tarone G, Turco E, Defilippi P., p130Cas is an essential transducer element in ErbB2 Transformation., FASEB J. 2010 Oct;24(10):3796-808. Epub 2010 May 26. PMID: 20505116.

• Sauzeau V, Berenjeno IM, Citterio C, Bustelo XR., A transcriptional cross-talk between RhoA and c-Myc inhibits the RhoA/Rock-dependent cytoskeleton. Oncogene. 2010 Jul 1;29(26):3781-92. Epub 2010 May 10.PMID: 20453885

• Lock JG, Strömblad S., Systems microscopy: an emerging strategy for the life sciences., Exp Cell Res. 2010 May 1;316(8):1438-44. Epub 2010 Apr 8. Review. PMID: 20381488.

• de Graauw M, van Miltenburg MH, Schmidt MK, Pont C, Lalai R, Kartopawiro J, Pardali E, Le Dévédec SE, Smit VT, van der Wal A, Van´t Veer LJ, Cleton-Jansen AM, Ten Dijke P, van de Water B., Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells. , Proceedings of the National Academy of Sciences of USA, 2010, Apr 6;107(14):6340-5. Epub 2010 Mar 22.

• Jokinen J, White DJ, Salmela M, Huhtala M, Käpylä J, Sipilä K, Puranen JS, Nissinen L, Kankaanpää P, Marjomäki V, Hyypiä T, Johnson MS, Heino J. Molecular mechanism of alpha2beta1 integrin interaction with human echovirus 1., the EMBO Journal,. January 2010.

• Ivaska J, Heino J., Interplay between cell adhesion and growth factor receptors: from the plasma membrane to the endosomes., Cell and Tissue Research, January 2010.

• Ruiz S, Santos E, Bustelo XR., The use of knockout mice reveals a synergistic role of the Vav1 and Rasgrf2 gene deficiencies in lymphomagenesis and metastasis., PLoS One. December 2009.

• Meves A., Stremmel C., Gottschalk K.E., and Fässler R (2009). The kindlin protein family: new members to the club of focal adhesion proteins, Trends in Cell Biol., October 2009.

• Böttcher R.T, Lange A., and Fässler R (2009). How ILK and kindlins cooperate to orchestrate integrin signaling. Curr. Opin. Cell Biol, October 2009.

• van Miltenburg MH, Lalai R, de Bont H, van Waaij E, Beggs H, Danen EH, van de Water B. Complete focal adhesion kinase deficiency in the mammary gland causes ductal dilation and aberrant branching morphogenesis through defects in Rho kinase-dependent cell contractility., FASEB J., October 2009.

• Sara Cabodi, Paola Di Stefano, Maria del Pilar Camocho Leal, Agata Tinnirelo, Brigitte Bisaro, Virginia Morello, Laura Damiano, Simona Aramu, Daniele Repetto, Giusy Tornillo and Paola Defilippi, Integrins and Signal Transduction, landes Bioscience, August 2009.

• Estecha A., Sánchez-Martín L., Puig-Kröger A., Bartolomé R.A., Teixidó J., Samaniego R., and Sánchez-Mateos P., Moesin orchestrates cortical polarity of melanoma tumour cells to initiate 3D invasion, Journal of Cell Science, July 2009.

• Martine H. A. M. van Miltenburg, Reshma Lalai, Hans de Bont, Eveline van Waaij, Hilary Beggs, Erik H. J. Danen, and Bob van de Water, Complete focal adhesion kinase deficiency in the mammary gland causes ductal dilation and aberrant branching morphogenesis through defects in Rho kinase-dependent cell contractility, FASEB Journal, July 2009